hiv

Bill and Melinda Gates Foundation / via Flickr

Even as momentum builds for an Ebola vaccine, researchers working to contain another virus say they’ve gotten their first big break in years. An older HIV vaccine candidate is showing new promise, and Seattle scientists will be leading a new trial of it early next year.

AP Photo/NIAID

A Seattle scientist is helping piece together the history of the HIV pandemic, and the new findings on when and where the pandemic began are helping explain how infectious diseases go global.

Courtesy of Bob Wood.

Editor's Note: “Senior Thesis” is a special week-long series that brings together venerable veterans in various fields with university students hoping to forge a career in the same field.

Bob Wood and Carolyn Wortham sat opposite each other in the KPLU studio, separated by a generation during which a whole lot had happened.

Between the time that Dr. Wood took up arms against the AIDS epidemic and when Wortham took on the same fight, the illness has gone from mysterious killer to manageable condition. The battlefield had moved, to some extent, from urban gay neighborhoods to the developing world.

bnilsen / Flickr

The Bill & Melinda Gates Foundation thinks safe sex isn’t as much fun as it should be.

At least, that seems to be the gist of one request for a grant application from the world’s largest philanthropy as part of its Grand Challenges Explorations program. One of the goals for this round is to develop a better condom.

“It is a bit unusual,” said Stephen Ward, the program officer with the Gates Foundation administering the project.

Alex Alonso / Flickr

A resurgence of AIDS among young men nationally is raising alarm bells – but not in the King County area.  Local health officials say outreach efforts here could be a model for how the rest of the country can keep the AIDS epidemic under control. 

GILEAD

The FDA today approved the first drug, known as Truvada, for preventing HIV in people at high risk of infection due to ‘discordance’ – science lingo for being HIV negative but having a sex partner who is HIV positive.

Seattle scientists played a critical role in demonstrating the drug’s effectiveness in Kenya and Uganda studies.

Read more on Humanosphere.

Top AIDS scientists are scratching their heads about new data from the most famous HIV patient in the world — at least to people in the AIDS community.

Timothy Ray Brown, known as the Berlin patient, is thought to be the first patient ever to be cured of HIV infection.

John Isaac / World Bank

A $258 million initiative sponsored by the Bill & Melinda Gates Foundation aimed at preventing AIDS in India appears to have paid off overall, researchers say, resulting in more than 100,000 fewer new HIV infections over five years.

Many aren’t quite ready to judge this project, Avahan, a success, however.

Read more on Humanosphere.

Thirty years ago this month, the first cases of AIDS were identified by the medical community. It was still a mystery disease. A strange form of pneumonia was striking young men in Los Angeles. Since then, the epidemic has been a dramatic roller-coaster of death, disease, politics and what some people call the greatest medical success story of the past half century. 

(This interactive timeline is from the federal AIDS.gov website. Click and scroll for dates and highlights.)

I sat down with Dr. Bob Wood, one of the most prominent local faces of AIDS and the fight to contain it, to discuss the highlights and low points. You can listen to the interview by clicking on "Audio."